Vol. 13 No. 4 (2026): October-December 2026

Original Research Articles

Comparative evaluation of dimensional changes achieved and osteopontin level in peri-implant crevicular fluid after sinus crestal floor elevation using piezosurgery and concentrated growth factor with or without allograft: a randomized clinical trial

Tanya Attre, Sumit Malhotra, Rebecca Chowdhry, Divya Gupta, Anoushka Pandey, Rahul Chopra

368-376

DOI: 10.18203/2349-3259.ijct20262785
- PDF
Evaluating the effect of cryotherapy on injection pain and onset of action of precooled and warmed local anesthetic agent in symptomatic irreversible pulpitis patients: an in vivo study

Anitha Rao S., Aravind Reddy V., Meghana Reddy J., Sree Satya Gayathri D., Jahnavi K., Laxmi Sri M., Parveen Fatima S. K., Sanjana B.

377-384

DOI: 10.18203/2349-3259.ijct20263253
- PDF
Comparative evaluation of perioperative multimodal analgesia and single-bolus epidural analgesia in lower abdominal surgery: a randomized controlled study

Jagriti, Manish Kumar, Anshu Singh, Ravi Kumar, Ajay Chaudhary

385-393

DOI: 10.18203/2349-3259.ijct20263753
- PDF
Comparative evaluation of caries removal using smart bur and ceramic bur in pediatric patients: an in vivo study

Muhammad Vajid C., Dhanya K. B., Ambili Ayilliath, Mridhul M. U.

394-401

DOI: 10.18203/2349-3259.ijct20263754
- PDF
Effect of fluoridated alcoholic and non-alcoholic mouth rinses on the load-deflection rate of orthodontic archwires: an in vitro study

Paridhi Jha, Vaibhav Misra, Rajeshwar Singh, Sonal Attri

402-408

DOI: 10.18203/2349-3259.ijct20263755
- PDF
Effect of choline-stabilized orthosilicic acid versus vitamins C and E on peri-implant procollagen type I N-terminal propeptide levels in smokers receiving dental implants: a randomized clinical study

Divya Gupta, Sumit Malhotra, Aruna Nautiyal, Tanya Attre, Anoushka Pandey, Rahul Chopra

409-417

DOI: 10.18203/2349-3259.ijct20262799
- PDF

Protocols

Coronary artery disease treatment strategies and long-term renal function: rationale and design of the cardiorenal study

Ezio De Martino Neto, Whady A. Hueb, Paulo C. Rezende, Lucas B. De Morais, Eduardo G. Lima, Paulo R. Soares, Fabio A. Venancio, Maria S. Tairova, Giovana Outuki, Izabela J. Martins, Carlos V. Serrano Junior, Jose A. F. Ramires, Roberto Kalil Filho

418-422

DOI: 10.18203/2349-3259.ijct20262800
- PDF
Efficacy of artificial intelligence‑integrated emotional granularity growth at improving resilience and quality of life in young and middle aged colorectal cancer survivors: protocol for a pilot randomised controlled trial

Jiyin Zhang, Joyce Oi Kwan Chung, Junjie Li, Weilin Chen, Yan Li, Janelle Yorke

423-435

DOI: 10.18203/2349-3259.ijct20263276
- PDF
The effect of back massage with mentholated ointment on pain and anxiety after coronary artery bypass graft surgery: a randomized controlled trial protocol

Muzeyyen Ataseven, Cagla Murali Tuna

436-441

DOI: 10.18203/2349-3259.ijct20263756
- PDF
Reliability and reproducibility of computed tomography-based facet joint measurements in patients with AO spine type A2, A3 and A4 thoracolumbar fractures: protocol for the REFACT study

Andrey Grin, Aleksandr Talypov, Anton Kordonskiy, Vasiliy Karanadze, Ivan Lvov, Mikhail Kucherov, Rinat Abdrafiev, Aleksandr Tupikin, Layla Khamidova, Roman Elokhovskiy, Ksenia Dmitrenko, Maria Nanoyan, Olga Minkina

442-446

DOI: 10.18203/2349-3259.ijct20263757
- PDF
Adaptive clinical trial with pharmacokinetic-guided optimization of weight-based oral montelukast dose in children with acute asthma exacerbations

Donald H. Arnold, Leonard B. Bacharier, James C. Slaughter, Theodore Reiss, Ashley Houser, James W. Antoon, Maria C. Balanta, Wendell S. Akers

447-454

DOI: 10.18203/2349-3259.ijct20263758
- PDF
Comparative efficacy of nebulised salbutamol, salbutamol plus budesonide and salbutamol plus fluticasone in the management of acute exacerbation of bronchial asthma in children: a study protocol of a randomized controlled trial

Rachna Pasi, Thirunavukkarasu Arun Babu

455-460

DOI: 10.18203/2349-3259.ijct20263759
- PDF
Efficacy of add-on Dusparshadi Kashaya and Chandraprabha Vati in the management of grade 2 to 3b chronic kidney disease: a structured study protocol of open labelled randomized standard controlled clinical trial

Thushari N. Alwis, Mandip R. Goyal

461-466

DOI: 10.18203/2349-3259.ijct20263760
- PDF
A study protocol for assessing the efficacy of add-on Brihatkataphaladi Vati, Vasadi Kashaya and polyherbal nebulization in the management of chronic obstructive pulmonary disease: a randomized placebo-controlled clinical trial

Maya Darji, Mandip R. Goyal

467-474

DOI: 10.18203/2349-3259.ijct20263761
- PDF
A study protocol for assessing the efficacy of Nagabala-Arjunadi Yoga and Arogyavardhini Rasa in the management of post-myocardial infarction as an add-on to the standard care: a standard controlled clinical trial

Palak R. Barvadia, Mandip Goyal

475-481

DOI: 10.18203/2349-3259.ijct20263762
- PDF

Review Articles

Bacterial DNA in joint tissue and its role in osteoarthritis: a narrative review

Aavrati Rastogi, Roop B. Kalia, Mukesh Bairwa

482-486

DOI: 10.18203/2349-3259.ijct20263763
- PDF
The role of artificial intelligence in clinical trials: opportunities

Vijaykumar Gawali

487-493

DOI: 10.18203/2349-3259.ijct20263764
- PDF
The evolving architecture of India’s clinical-trial rules, 2019-2026: a chronological appraisal and stakeholder analysis of the New Drugs and Clinical Trials Rules and their amendments

Amrita Sankhe, Vijaykumar Gawali, Maria Franco

494-500

DOI: 10.18203/2349-3259.ijct20263765
- PDF
Negligence without a patient: medical negligence in clinical trials in India and the comparative study of South Korea and Australia

Abhinav Kuchipudi, Aditi Jani

501-508

DOI: 10.18203/2349-3259.ijct20263766
- PDF

Original Research Articles

Comparative evaluation of dimensional changes achieved and osteopontin level in peri-implant crevicular fluid after sinus crestal floor elevation using piezosurgery and concentrated growth factor with or without allograft: a randomized clinical trial

Evaluating the effect of cryotherapy on injection pain and onset of action of precooled and warmed local anesthetic agent in symptomatic irreversible pulpitis patients: an in vivo study

Comparative evaluation of perioperative multimodal analgesia and single-bolus epidural analgesia in lower abdominal surgery: a randomized controlled study

Comparative evaluation of caries removal using smart bur and ceramic bur in pediatric patients: an in vivo study

Effect of fluoridated alcoholic and non-alcoholic mouth rinses on the load-deflection rate of orthodontic archwires: an in vitro study

Effect of choline-stabilized orthosilicic acid versus vitamins C and E on peri-implant procollagen type I N-terminal propeptide levels in smokers receiving dental implants: a randomized clinical study

Protocols

Coronary artery disease treatment strategies and long-term renal function: rationale and design of the cardiorenal study

Efficacy of artificial intelligence‑integrated emotional granularity growth at improving resilience and quality of life in young and middle aged colorectal cancer survivors: protocol for a pilot randomised controlled trial

The effect of back massage with mentholated ointment on pain and anxiety after coronary artery bypass graft surgery: a randomized controlled trial protocol

Reliability and reproducibility of computed tomography-based facet joint measurements in patients with AO spine type A2, A3 and A4 thoracolumbar fractures: protocol for the REFACT study

Adaptive clinical trial with pharmacokinetic-guided optimization of weight-based oral montelukast dose in children with acute asthma exacerbations

Comparative efficacy of nebulised salbutamol, salbutamol plus budesonide and salbutamol plus fluticasone in the management of acute exacerbation of bronchial asthma in children: a study protocol of a randomized controlled trial

Efficacy of add-on Dusparshadi Kashaya and Chandraprabha Vati in the management of grade 2 to 3b chronic kidney disease: a structured study protocol of open labelled randomized standard controlled clinical trial

A study protocol for assessing the efficacy of add-on Brihatkataphaladi Vati, Vasadi Kashaya and polyherbal nebulization in the management of chronic obstructive pulmonary disease: a randomized placebo-controlled clinical trial

A study protocol for assessing the efficacy of Nagabala-Arjunadi Yoga and Arogyavardhini Rasa in the management of post-myocardial infarction as an add-on to the standard care: a standard controlled clinical trial

Review Articles

Bacterial DNA in joint tissue and its role in osteoarthritis: a narrative review

The role of artificial intelligence in clinical trials: opportunities

The evolving architecture of India’s clinical-trial rules, 2019-2026: a chronological appraisal and stakeholder analysis of the New Drugs and Clinical Trials Rules and their amendments

Negligence without a patient: medical negligence in clinical trials in India and the comparative study of South Korea and Australia

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