Interplay between psychological resilience and emotional burden in knee osteoarthritis: a cross-sectional analysis of pain perception and functional disability
DOI:
https://doi.org/10.18203/2349-3259.ijct20262504Keywords:
Knee osteoarthritis, Psychological resilience, Depression, Anxiety, WOMAC, Functional disabilityAbstract
Background: Knee osteoarthritis (OA) is a common cause of chronic pain and functional disability, frequently associated with psychological distress. Emotional burden, including depression and anxiety, may exacerbate symptoms, while psychological resilience may act as a protective factor.
Methods: A cross-sectional study was conducted among 108 patients aged 45–70 years with clinically diagnosed knee OA, according to EULAR diagnostic criteria. The mean age of patients was 55.92±0.8 years, and the mean BMI was 27.24±0.4 kg/m2. Emotional burden was assessed using the PHQ-9 and GAD-7, and resilience using the brief resilience scale. Functional disability and pain were evaluated using the WOMAC index. Pearson correlation analysis was performed.
Results: Mean scores for depression, anxiety, and resilience were 8.97±5.93, 9.35±5.97, and 20.33±7.11, respectively. Depression showed no significant correlation with functional disability (r=0.04, p=0.69). Anxiety (r=-0.18, p=0.07) and resilience (r=-0.17, p=0.09) demonstrated weak inverse correlations with WOMAC scores.
Conclusions: Although not statistically significant, consistent inverse trends suggest a potential role of psychological factors in functional outcomes, supporting a multidimensional approach to knee OA management, including psychological assessment and intervention.
References
Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ. 2003;81(9):646-56.
Bennell KL, Hinman RS. Osteoarthritis year in review. Osteoarthritis Cartilage. 2016;24(1):58-70.
Axford J, Heron C, Ross F, et al. Prevalence of psychiatric disorders in OA. Ann Rheum Dis. 2010;69(3):443–448.
Rosemann T, Backenstrass M, Joos S, et al. Predictors of depression in OA. Arthritis Rheum. 2007;57(3):415–422.
Bradshaw DH, Richardson GE, Kumpfer K. Anxiety and chronic pain. Pain Med. 2007;8(6):549-58.
Tugade MM, Fredrickson BL. Psychological resilience and coping. J Pers Soc Psychol. 2004;86(2):320-33.
Kusko DA, Thomas PA, Addison A, Quinn TL, Gonzalez CE, Sibille KT, et al. An Examination of Psycho-Behavioral Risk and Resilience in People with Chronically Painful Knee Osteoarthritis. J Pain. 2024;25(4):24.
Sayre EC, Esdaile JM, Kopec JA, Singer J, Wong H, Thorne A, et al. Specific manifestations of knee osteoarthritis predict depression and anxiety years in the future: Vancouver Longitudinal Study of Early Knee Osteoarthritis. BMC Musculoskeletal Disorders. 2020;21(1):46.
Caya R, Christopherson RM, Pierobon A, Abbott JH, Skou ST, Haase AM, et al. Does mental health mediate the effect of nonsurgical exposures on pain and functional outcomes in osteoarthritis? A systematic review. Osteoarthritis Cartilage. 2026;34(8):1176-83.
GBD 2021 Osteoarthritis Collaborators. Global, regional, and national burden of osteoarthritis, 1990-2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023;5(9):e508-22.
Somers TJ, Keefe FJ, Pells JJ, Dixon KE, Waters SJ, Riordan PA, et al. Pain catastrophizing and pain-related fear in osteoarthritis patients: relationships to pain and disability. J Pain Symptom Management. 2009;37(5):863-72.
Pan F, Jones G. Clinical perspective on pain and pain phenotypes in osteoarthritis. Curr Rheumatol Rep. 2018;20(12):79.
Matcham F, Rayner L, Steer S, Hotopf M. The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis. Rheumatology. 2013;52(12):2136-48.
Chng Z, Yeo JJ, Joshi A. Resilience as a protective factor in the face of pain symptomatology, disability, and psychological outcomes in adult chronic pain populations: a scoping review. Scand J Pain. 2023;23(2):228-50.
Meng J, Cai Y, Yao J, Yan H. Bidirectional causal relationship between psychiatric disorders and osteoarthritis: a univariate and multivariate Mendelian randomization study. Brain Behav. 2024;14:e3429.
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