Clinical trials unveiled: an overview of key concepts, strategies and challenges

Authors

  • Lingaraj Mishra ICMR-Regional Medical Research Center, Chandrasekhapur, Bhubaneswar, Odisha, India
  • Priyanka Priyadarshini Pattnaik Department of Pulmonary Medicine (Superspeciality-DM), Sri Ramchandra Bhanja Medical College and Hospital, Cuttack, Odisha, India
  • Manoranjan Pattnaik Department of Pulmonary Medicine (Superspeciality-DM), Sri Ramchandra Bhanja Medical College and Hospital, Cuttack, Odisha, India
  • Jeetendra Kumar Patra Department of Pulmonary Medicine (Superspeciality-DM), Sri Ramchandra Bhanja Medical College and Hospital, Cuttack, Odisha, India
  • Sanghamitra Pati ICMR-Regional Medical Research Center, Chandrasekhapur, Bhubaneswar, Odisha, India
  • Shashikanta Nayak ICMR-Regional Medical Research Center, Chandrasekhapur, Bhubaneswar, Odisha, India

DOI:

https://doi.org/10.18203/2349-3259.ijct20250135

Keywords:

Clinical trials, Inform consent, Impartial witness, Inform assent, Legally acceptable representative, Medical science, Regulatory

Abstract

Carrying out clinical trials is essential for pushing forward the cause of medical science in that such is a stance from which it is possible to provide the proofs necessary for sanctioning new treatment methods including making sure they are safe and generally efficient. Clinical research help researcher to discover new medications to treat, prevention, mitigation of prevailing disease. Because of clinical trial many effective treatments in field of disease, vaccines are available which are quite more effective than the marketed drugs. It can also be said that the clinical research would not be successful without participating subjects. The participating volunteers are irrespective of healthy or have a medical condition. People of any age and backgrounds can participate in the trial. Usually, clinical trials are characterized by multiple problems such as poor recruitment, ethical problems, regulatory issues, and exorbitant prices. The present paper gives a glimpse of the manner in which clinical trials are usually followed, the stages that are typically covered throughout, not forgetting, the most crucial barriers which are involved.

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References

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Published

2025-01-28

How to Cite

Mishra, L., Pattnaik, P. P., Pattnaik, M., Patra, J. K., Pati, S., & Nayak, S. (2025). Clinical trials unveiled: an overview of key concepts, strategies and challenges. International Journal of Clinical Trials, 12(1), 69–73. https://doi.org/10.18203/2349-3259.ijct20250135

Issue

Section

Review Articles