Perioperative management of hyperglycemic patients undergoing surgery: an observational cross sectional study in a tertiary care hospital
DOI:
https://doi.org/10.18203/2349-3259.ijct20242000Keywords:
Corticosteroids, Intravenous fluids, Blood sugar control, Anaesthesia, DiabetesAbstract
Background: Diabetes poses an additional risk during anesthesia, yet there is a lack of sufficient Indian data on perioperative antidiabetic drug use and its implications. This droves us to conduct the study.
Methods: Cross-sectional, observational study, conducted in a tertiary care hospital's general surgery and orthopaedics wards. Data collected from the first anaesthetist visit to 24 hours postoperative period included antidiabetic medications, anesthesia drugs, blood sugar levels, co-morbidities, concomitant medications, and intravenous (IV) fluids. Descriptive statistics and parametric tests were used for analysis.
Results: The study comprised 180 patients (62.8% males, median age 56 years), with diabetes duration predominantly between 1-5 years (28.3%). Preoperatively, metformin was the most prescribed oral hypoglycemic agent (72.2%), decreasing to 56.67% postoperatively. Intraoperatively, only 1.6% received insulin, while 98.4% received no drugs. Common postoperative antidiabetic agents included insulin BD (n=48). General surgery (73.3%) and orthopedics (26.7%) contributed 132 and 48 patients, respectively, with spinal anesthesia (68.3%) and bupivacaine (75.4%) being most prevalent. Blood glucose during surgery was effectively monitored. Hypertension (52.8%) was the most common co-morbidity, and Ringer lactate (60.8%) was the predominant IV fluid.
Conclusions: Adequate perioperative antidiabetic management was observed in hyperglycemic patients.
Metrics
References
Khan MAB, Hashim MJ, King JK, Govender RD. Epidemiology of Type 2 Diabetes-Global Burden of Disease and Forecasted Trends. J Epidemiol Glob Health. 2020;10(1):107-11.
Diabetes among senior citizens more prevalent in urban India: LASI report. Available at: https://www.iipsindia.ac.in/sites/default/files/news_documents/LASI_W1-Diabetes_among_senior_citizens_more_prevalent_in_urban_India.pdf. Accessed on 14 February, 2024.
Bansal N. Prediabetes diagnosis and treatment: A review. World J Diabetes. 2015;6(2):296-303.
Papatheodorou K, Banach M, Bekiari E, Rizzo M, Edmonds M. Complications of Diabetes 2017. J Diabetes Res. 2018;3086167.
Chen WQ, Wong TW, Yu TS. Review Article: Influence of occupational stress on mental health among Chinese off-shore oil workers. Scand J Public Health. 2009;37(7):766-73.
Annual report. 2020. Website of institution. Available at: https://www.Instituition.edu/wpcontent/ uploads/2021/04/instituition_AR_2020.pdf. Accessed on 11 February 2024.
Nordström A, Hadrévi J, Olsson T, Franks PW, Nordström P. Higher Prevalence of Type 2 Diabetes in MenThan in Women Is Associated with Differences in Visceral Fat Mass. J Clin Endocrinol Metab. 2016;101(10):3740-6.
Long AN, Dagogo-Jack S, Comorbidities of Diabetes and Hypertension: Mechanisms and Approach to Target Organ Protection. J Clin Hypertens. 2011;13(4):244.
Padwal R, Laupacis A. Antihypertensive Therapy and Incidence of Type 2 Diabetes A systematic review. Diabetes Care. 2004;27(1):247-55.
Jackson MJ, Patvardhan C, Wallace F. Perioperative management of diabetes in elective patients: A regionwide audit. Br J Anaesth. 2016;116(4):501-6.
Scheuer C, Boot E, Carse N. Study on prescribing pattern of anti-diabetic drugs among type 2 diabetes patients with complication in South Indian teaching hospital. Asian J Pharm Clin Res. 2016;9:194-7.
Ghandi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, et al. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial. Ann Intern Med. 2007;146(4):233-43.
Setji TL, Gilmore L, Freeman S. Perioperative diabetes management. Diabetes Manag. 2018;8(3):67-73.
Cheisson G, Jacqueminet S, Cosson E, Ichai C, Anne-Marie L, Bogdan NC, et al. Perioperative management of adult diabetic patients. Preoperative period. Anaesth Crit Care Pain Med. 2018;37(1):S9-19.
Đinđić N, Zlatković-Guberinić S, Sokolović D, Kocić R, Veličković-Radovanović R, Damnjanović I, et al. Influence of beta-blockers on insulin resistance in patients with diabetes mellitus type 2. Acta Medica Median, 2011;50(4):23-8.
Suh S, Park MK. Glucocorticoid-Induced Diabetes Mellitus: An Important but Overlooked Problem. Endocrinol Metab. 2017;32(2):180.
Hoorn EJ. Intravenous fluids: balancing solutions. J Nephrol. 2020;33(2):387.