Study of correlation between gallstones and bactibilia

Abstract

Background: Now a days Cholecystectomy is one of the commonly performed operations. Most common cause is Gallstones. So, we planned this study to determine to find out any association between gallstone and microbiological spectrum in bile in cholelithiasis patients undergoing laparoscopic or open cholecystectomy.

Methods: Total 140 patients of chronic calculous cholecystitis admitted in the department of general surgery, KPC medical college & hospital, Jadavpur, Kolkata, during August 2021 to July 2022 for cholecystectomy were included in this study. All patients underwent either laparoscopic or open cholecystectomy. During cholecystectomy bile was collected and sent to the department of microbiology for bacteriological profile of bile. Gallstone is classified based on morphology following gallstone retrieved from the gall bladder.

Results: Out of 140 cases 115 cases done laparoscopic cholecystectomy and 25 cases done open cholecystectomy. In this study bile culture test negative in 105 cases and positive in 35 of cases. Escherichia coli was the most common micro-organism found in 20 cases, Enterococcus species in 8 cases, in 5 cases Staphylococcus aureus and 2 mixed infections. In culture negative case mostly gallstones were larger, 2 to 3 in number and yellowish in colour. In culture positive cases mostly, gallstone was more than 3 in number, smaller, black and brown in colour.

Conclusions: In the light of above obtained results, the authors concluded that multiple, small, dark and brown in colour gallstone in cholelithiasis patients often show bactibilia. The low incidence of bacterbilia may suggest restriction of use of antibiotics in mild biliary pain.